Manufacturer makes no specific recommendation. Adults 18 years and older Pneumonia, community-acquired - mg every 12 hours for 5 days PI. Take at least 1 hour before a meal or 2 hours after a meal. Strong and moderate CYP3A4 inducers may decrease the effectiveness of lefamulin. Do not take lefamulin with strong CYP3A4 inhibitors. Monitor for adverse effects when taking with moderate CYP3A4 inhibitors. Lefamulin is a P-glycoprotein substrate.
P-glycoprotein inducers may decrease the effectiveness of lefamulin. Do not take with strong P-glycoprotein inhibitors. Monitor for adverse effects when taking with moderate P-glycoprotein inhibitors.
Lefamulin can prolong the QT interval. Avoid use in patients with prolonged QT syndrome and in those taking concomitant medications that can prolong the QT interval. Not recommended. Kidney disease - no dose adjustment necessary. Do not take within 2 weeks of other MAO inhibitors. May increase the pressor effect of adrenergic agents including pseudoephedrine and phenylpropanolamine. Foods containing tyramine should also be avoided in large quantities e. Do not use with other serotonergic agents unless no other options are available.
If concomitant therapy is necessary, monitor for symptoms of serotonin syndrome for two weeks five weeks if fluoxetine was taken or until 24 hours after the last dose of linezolid, whichever comes first. Linezolid susceptibility testing in [PubMed abstract] - 6, Gram-positive pathogens from 36 states collected in were tested for susceptibility to linezolid.
Linezolid demonstrated excellent activity and a sustained susceptibility rate of May take without regard to food For a missed dose, take as soon as possible anytime up to 8 hours prior to the next scheduled dose.
If less than 8 hours remain before the next dose, wait until next scheduled dose. Tedizolid is a BCRP inhibitor and may increase exposure to BCRP substrates May increase the pressor effect of adrenergic agents including pseudoephedrine and phenylpropanolamine. Use caution when taken with antidepressants and other serotonergic drugs. Liver disease - no dose adjustment necessary Kidney disease - no dose adjustment necessary. Ophthalmic See conjunctivitis.
Use azithromycin. Adults Bordetella pertussis treatment or postexposure prophylaxis - mg twice a day for 7 days CDC Endocarditis prophylaxis - mg 30 - 60 minutes before procedure penicillin allergic AHA H. Standard-release tablet and suspension may be taken without regard to food. Extended-release tablets should be taken with food. See Biaxin PI for more. Topical See topical derm meds. Tablet E.
Suspension E. Dosing is for erythromycin base. Azithromycin is the preferred agent in this age group. May take without regard to food mg of erythromycin ethylsuccinate is equivalent to mg of erythromycin base or stearate Erythromycin is a Moderate CYP3A4 inhibitor Erythromycin is contraindicated with lovastatin and simvastatin Liver disease - use caution.
Kidney disease - erythromycin is mostly excreted in the bile. May take without regard to food After granules are reconstituted, they should be refrigerated and are good for up to 12 days Fidaxomicin undergoes minimal absorption and should not be used for systemic infections Liver disease - fidaxomicin undergoes minimal absorption.
Liver disease should not affect. Take with food. Food increases absorption. Apply market research to generate audience insights. Measure content performance. Develop and improve products.
List of Partners vendors. If you or your child has ever needed to take an antibiotic for a bacterial infection, there's a good chance the medication prescribed was either amoxicillin or Augmentin amoxicillin clavulanate.
A common assumption about these two medications is that Augmentin is simply a stronger version of amoxicillin but that isn't quite accurate. Augmentin contains a second active ingredient, which makes it more appropriate for treating certain infections than others. The same holds true for amoxicillin and, to make the distinctions between the drugs even hazier, there are a few infections that both treat equally effectively.
Ultimately, the antibiotic a healthcare provider prescribes will depend on the type of illness being treated and the bacteria responsible for it.
Amoxicillin is often the first antibiotic prescribed for common bacterial infections, particularly those that cause illness in children, such as ear, nose, and throat infections, including tonsillitis.
This antibiotic also is the first drug of choice for:. Note that although amoxicillin can kill many of the same bacteria as penicillin, it is less effective than penicillin against Streptococcus pneumococcus, the bacteria commonly associated with meningitis and systemic bacteremia. The side effects of amoxicillin tend to be relatively mild, which is another reason it's often prescribed for kids.
The most common ones include rash, vaginal itching, and a dark or "hairy tongue. As with penicillin, there is a risk of an allergic reaction to amoxicillin in those predisposed to it. These can be life-threatening. It's vital a healthcare provider take a medical history before prescribing amoxicillin to determine if a patient has a known history of allergy to antibiotics.
Augmentin is amoxicillin combined with a beta-lactamase inhibitor called clavulanate, an ingredient that blocks the enzymes that contribute to antibiotic resistance.
The addition of a beta-lactamase blocker to amoxicillin allows Augmentin to overcome resistance to harder-to-treat bacteria, broadening the spectrum of infections it can treat. It is for this reason that Augmentin is referred to as a broad-spectrum antibiotic. Augmentin can treat the same bacteria as amoxicillin, but also is effective against certain harder-to-treat infections, including:. It should be noted there are a few infections for which amoxicillin and Augmentin are prescribed equally:.
This photo contains content that some people may find graphic or disturbing. The most common side effect of Augmentin is diarrhea. Some people may also experience nausea, vomiting, yeast infections, and rash. If you have an infection and don't necessarily know which bacteria is causing it, it may seem to make sense to use an antibiotic that would kill the most bugs. However, doing that can cause major problems.
Antibiotics used indiscriminately may destroy "good" bacteria along with "bad," thereby altering the body's natural flora and allowing even worse bacteria to proliferate. Another, even more pressing concern is that using broad-spectrum antibiotics can lead to antibiotic resistance. When this happens, a few mutated bacteria may survive, some of which may be naturally resistant to the antibiotic you were taking. Both cefdinir and amoxicillin can interact with anti-gout medications like probenecid and allopurinol.
Anti-gout agents can increase the blood levels of cefdinir and amoxicillin, which can lead to increased side effects. Cefdinir and amoxicillin have been known to cause prolonged prohrombin time in those who are also taking warfarin.
This drug interaction can cause an increased risk of bleeding. Antibiotics have been known to decrease the effectiveness of oral contraceptives. Alternate birth control methods may be needed to reduce the risk of pregnancy. This may not be a complete list of all possible drug interactions.
Consult a doctor with all the medications you may be taking. Cefdinir and amoxicillin should be avoided if you have a penicillin allergy.
Because these drugs are chemically similar to penicillin, they may cause a severe allergic reaction if you have an established penicillin allergy.
Diarrhea is one of the most common side effects of antibiotics like cefdinir and amoxicillin. These antibiotics can also increase the risk of a more severe type of diarrhea caused by Clostridium difficile. If you have a medical history of C. These antibiotics should only be prescribed for infections caused by bacteria. Cefdinir and amoxicillin are most effective when they are targeting susceptible bacteria. If they are used inappropriately, the bacteria can gain antibiotic resistance and cause a more severe infection.
Cefdinir is a third-generation cephalosporin that is used to treat bacterial infections like acute otitis media and pharyngitis. It is also FDA-approved to treat certain skin infections and lower respiratory tract infections. Cefdinir is also known by its brand name Omnicef.
Amoxicillin is a penicillin-type antibiotic that is used to treat various bacterial infections of the ear, nose, and throat. It can also treat lower respiratory tract infections, H. Amoxicillin is often combined with clavulanate, or clavulanic acid, under the brand name Augmentin. Cefdinir and amoxicillin are not the same. The more effective antibiotic is the one that works best against the bacterial strain causing the infection.
For example, amoxicillin is better for H. However, some people may prefer cefdinir in a once-daily option for other infections. There have been no adequate clinical studies to show that cefdinir or amoxicillin are safe while pregnant.
They are both deemed Pregnancy Category B drugs, which indicates a low risk for birth defects. Still, they should only be used if necessary. Consult a healthcare provider for medical advice on the best option during pregnancy. Alcohol does not directly interact with cefdinir or amoxicillin.
However, it is not generally recommended to drink alcohol with antibiotics.
0コメント